CilioGenics is an integrated and open source, community friendly database for ciliary genes. The key goal is to combine a variety of cilia-related data, including single-cell RNA-seq, comparative genomics, aggregation of gene list from cilia-related publications, protein atlas, proteomics, and cilia-specific motifs. Gene search is quick and user friendly, and it connects to a page devoted to the specific gene, which displays a variety of cilia-related information about that gene.
CilioGenics also provides a number of resources to:
explore the evolutionary dynamics ( the comparative genomics) of each gene in the interactive heatmap
explore the expression patterns of each gene (whole organisms in C. elegans, and lung tissue in human)
view proteomics relationship between ciliary proteins and other proteins
search for the name of gene in each cilia related publications
Cilia are a complex organelle that possibly house hundreds of various proteins, and CilioGenics is a user-friendly database that aims to provide all existing knowledge about a gene. An automatic update is introduced into CilioGenics. For example, proteomics database BioGRID is automatically updated when a new update from BioGRID is released. However, since any effort to reveal the full constituents of cilia by one technique or a combination of two techniques is likely to fail to catch the entire ciliary genes and there will always new data about a gene, please help us to update the website if you have new data about a gene(s), as CilioGenics strives to incorporate new emerging data about each gene.
We would be glad if you would contribute to expanding and improving the CilioGenics database. Here are a few ways you can help CilioGenics:
Submit a new paper presenting the ciliary gene list or single-cell RNA-seq paper.
Please submit a paper that is not currently in the CilioGenics collection, along with a brief description of the paper, such as a DOI for the paper and/or the integration table number. Please email us if you are willing to submit previously unpublished work.
Update existing data on the CilioGenics
Please consider submitting a feedback if you find any missing or incorrect information.
CilioGenics is a dynamic and a constantly updated database, and if a major update is made, a new version of the database will be made available.
Please contact oktay.kaplan@agu.edu.tr or mustafapir29@gmail.com for any question or inquiries.
For source code of the website: thekaplanlab/CilioGenics-website (github.com)